Open AccessIdentification of Amino Acids within Nonstructural Proteins 10 and 14 of the Avian Coronavirus Infectious Bronchitis Virus That Result in Attenuation In Vivo and In Ovo
Author(s) -
Sarah Keep,
Phoebe Stevenson-Leggett,
Giulia Dowgier,
Holly Everest,
Graham Freimanis,
Michael S Oade,
John A. Hammond,
María Armesto,
R. Vila,
T. Bru,
Harm J. Geerligs,
Paul Britton,
Erica Bickerton
Publication year - 2022
Publication title -
journal of virology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.617
H-Index - 292
eISSN - 1070-6321
pISSN - 0022-538X
DOI - 10.1128/jvi.02059-21
Subject(s) - in ovo , biology , embryonated , infectious bronchitis virus , virology , avian infectious bronchitis , attenuated vaccine , avian infectious bronchitis virus , nidovirales , virulence , virus , infectious dose , coronavirus , reverse genetics , vaccination , serial passage , microbiology and biotechnology , gene , genetics , infectious disease (medical specialty) , mutant , embryo , disease , medicine , covid-19 , pathology
TheGammacoronavirus infectious bronchitis virus (IBV) is the etiological agent of infectious bronchitis, an acute, highly contagious, economically important disease of poultry. Vaccination is achieved using a mixture of live attenuated vaccines for young chicks and inactivated vaccines as boosters for laying hens.