Open AccessAntibody-Based Inhibition of Pathogenic New World Hemorrhagic Fever Mammarenaviruses by Steric Occlusion of the Human Transferrin Receptor 1 Apical Domain
Author(s) -
Sol Ferrero,
Maria D. Flores,
Connor Short,
Cecilia Vázquez,
Lars E. Clark,
James Ziegenbein,
Samantha Zink,
Daniel Fuentes,
Cristian Payés,
María Victoria Batto,
Michael Collazo,
Cybele C. Garcı́a,
Jonathan Abraham,
Sandra M. Cordo,
José A. Rodríguez,
Gustavo Helguera
Publication year - 2021
Publication title -
journal of virology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.617
H-Index - 292
eISSN - 1070-6321
pISSN - 0022-538X
DOI - 10.1128/jvi.01868-20
Subject(s) - ectodomain , biology , arenavirus , virology , junin virus , monoclonal antibody , virus , antibody , antigen , biochemistry , lymphocytic choriomeningitis , receptor , genetics , cd8
Pathogenic clade B NWMs cause grave infectious diseases, the South American hemorrhagic fevers. Their etiological agents are Junin (JUNV), Guanarito (GTOV), Sabiá (SABV), Machupo (MACV), Chapare (CHAV), and a new Sabiá-like (SABV-L) virus recently identified in Brazil.
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