Open AccessThe Long and Complicated Relationship between Epstein-Barr Virus and Epithelial Cells
Author(s) -
Lindsey HuttFletcher
Publication year - 2016
Publication title -
journal of virology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.617
H-Index - 292
eISSN - 1070-6321
pISSN - 0022-538X
DOI - 10.1128/jvi.01677-16
Subject(s) - biology , virus , virology , epstein–barr virus , persistence (discontinuity) , viral replication , geotechnical engineering , engineering
The roles of epithelial cells in infection and persistence of the Epstein-Barr virus (EBV) have long been difficult to resolve. However, recent developments have reinforced the conclusion that these cells are a major site of virus replication and raised the possibility that, like papillomaviruses, EBV has evolved to take advantage of epithelial differentiation to ensure survival, persistence, and spread.
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