Sequence Variability of Human Erythroviruses Present in Bone Marrow of Brazilian Patients with Various Parvovirus B19-Related Hematological Symptoms
Author(s) -
Sabri Saeed Sanabani,
Walter Kleine Neto,
Juliana Pereira,
Éster Cerdeira Sabino
Publication year - 2006
Publication title -
journal of clinical microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.349
H-Index - 255
eISSN - 1070-633X
pISSN - 0095-1137
DOI - 10.1128/jcm.44.2.604-606.2006
Subject(s) - genotype , parvovirus , phylogenetic tree , biology , bone marrow , parvoviridae , virology , cluster (spacecraft) , polymerase chain reaction , immunology , genetics , virus , gene , computer science , programming language
The presence of erythrovirus infections was investigated by PCR with bone marrow samples of patients with various parvovirus B19-related hematological symptoms. Erythrovirus DNA was found in 17.3% (12/69) of patients. Phylogenetic analysis revealed that five strains cluster with genotype 1, one clusters with genotype 2, and six cluster with genotype 3. Our study is the first to document the presence of the three erythrovirus genotypes in Brazil.
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