Open AccessDecreased Prevalence of Virulence Factors among Ciprofloxacin-Resistant Uropathogenic Escherichia coli Isolates
Author(s) -
Steven J. Drews,
Susan M. Poutanen,
Tony Mazzulli,
Allison McGeer,
Alicia Sarabia,
Sylvia Pong-Porter,
Y. Rzayev,
Barbara M. Willey,
K. Green,
Donald E. Low
Publication year - 2005
Publication title -
journal of clinical microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.349
H-Index - 255
eISSN - 1070-633X
pISSN - 0095-1137
DOI - 10.1128/jcm.43.8.4218-4220.2005
Subject(s) - ciprofloxacin , escherichia coli , microbiology and biotechnology , virulence , fimbria , genotype , urinary system , biology , outpatient clinic , medicine , gene , antibiotics , genetics
Ciprofloxacin resistance was identified in 18% and 6% of consecutively collected, clinically significant urinary tract isolates ofEscherichia coli from inpatients and outpatients, respectively. In comparison to ciprofloxacin-susceptible isolates, there were fewer resistant isolates that expressed beta-hemolysis (outpatient, 9% versus 87%,P < 0.0001; inpatient, 4% versus 76%,P < 0.0001) and that had apapEF genotype, genes encoding P fimbriae (outpatient, 30% versus 70%,P = 0.0004; inpatient, 26% versus 70%,P < 0.0001).