
Identification and Characterization of Genomic Variations between Mycobacterium bovis and M. tuberculosis H37Rv
Author(s) -
Ariel Amadio,
Maria Romanò,
Fabiana Bigi,
Ignacio Etchechoury,
Tanja Kubica,
Stefan Niemann,
Angel Cataldi,
Karina Caimi
Publication year - 2005
Publication title -
journal of clinical microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.349
H-Index - 255
eISSN - 1070-633X
pISSN - 0095-1137
DOI - 10.1128/jcm.43.5.2481-2484.2005
Subject(s) - mycobacterium bovis , tuberculosis , mycobacterium tuberculosis complex , biology , gene duplication , mycobacterium tuberculosis , genetics , microbiology and biotechnology , identification (biology) , gene , medicine , pathology , botany
Genetic differences between Mycobacterium bovis and M. tuberculosis were identified. We found (i) a deletion of Rv3479 specific to M. bovis, (ii) that the rpfA gene is shortened to various extents in M. bovis, and (iii) an insertion in Rv0648 and a duplication of lppA common in M. tuberculosis complex isolates.