Open AccessFusarium verticillioides Abscess of the Nasal Septum in an Immunosuppressed Child: Case Report and Identification of the Morphologically Atypical Fungal Strain
Author(s) -
Hans Jürgen Dornbusch,
Walter Buzina,
Richard C. Summerbell,
Cornelia LassFlörl,
Herwig Lackner,
Wolfgang Schwinger,
Petra Sovinz,
Christian Urban
Publication year - 2005
Publication title -
journal of clinical microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.349
H-Index - 255
eISSN - 1070-633X
pISSN - 0095-1137
DOI - 10.1128/jcm.43.4.1998-2001.2004
Subject(s) - amphotericin b , biology , fusarium , abscess , microbiology and biotechnology , ribosomal rna , pathology , gene , medicine , antifungal , genetics
Morphologically atypical Fusarium verticillioides causing a nasal abscess in a severely immunosuppressed child was successfully treated with repeated surgical intervention and liposomal amphotericin B, despite amphotericin B resistance in vitro. Definitive identification was achieved by sequencing the translation elongation factor alpha gene after ribosomal sequencing proved inadequate.