Open AccessFrequency and Species Distribution of Gliotoxin-Producing Aspergillus Isolates Recovered from Patients at a Tertiary-Care Cancer Center
Author(s) -
Russell E. Lewis,
Nathan P. Wiederhold,
Michail S. Lionakis,
Randall A. Prince,
Dimitrios P. Kontoyiannis
Publication year - 2005
Publication title -
journal of clinical microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.349
H-Index - 255
eISSN - 1070-633X
pISSN - 0095-1137
DOI - 10.1128/jcm.43.12.6120-6122.2005
Subject(s) - tertiary care , aspergillus , gliotoxin , microbiology and biotechnology , biology , cancer , center (category theory) , aspergillus fumigatus , medicine , chemistry , crystallography
Aspergillus isolates (n = 103) collected from cancer patients were screened to determine the taxonomic distribution and quantity of gliotoxin production. Gliotoxin was detected in 93% ofAspergillus fumigatus , 75% ofA. niger , 25% ofA. terreus , and 4% ofA. flavus cultures. Gliotoxin concentrations were highest in cultures ofA. fumigatus .