Open AccessMolecular Identification of Rhizomucor pusillus as a Cause of Sinus-Orbital Zygomycosis in a Patient with Acute Myelogenous Leukemia
Author(s) -
Peter C. Iwen,
Alison G. Freifeld,
Lynne Sigler,
Stefano Tarantolo
Publication year - 2005
Publication title -
journal of clinical microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.349
H-Index - 255
eISSN - 1070-633X
pISSN - 0095-1137
DOI - 10.1128/jcm.43.11.5819-5821.2005
Subject(s) - zygomycosis , biology , mucormycosis , leukemia , microbiology and biotechnology , pathology , medicine , genetics , amphotericin b , antifungal
Sinus-orbital zygomycosis caused byRhizomucor pusillus in a patient with acute myelogenous leukemia is described. Identification was achieved by sequencing of the internal transcribed spacer (ITS) regions of the rRNA gene and by expression of zygospores in mating. This report highlights the value of ITS sequencing as a diagnostic tool for the identification ofR. pusillus and expands the understanding of infection types caused by this zygomycete.