Open AccessDistribution of Strain Families ofMycobacterium tuberculosisCausing Pulmonary and Extrapulmonary Disease in Hospitalized Children in Cape Town, South Africa
Author(s) -
Mark P. Nicol,
Christophe Sola,
Bradley February,
Nalin Rastogi,
Lafras M. Steyn,
Robert J. Wilkinson
Publication year - 2005
Publication title -
journal of clinical microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.349
H-Index - 255
eISSN - 1070-633X
pISSN - 0095-1137
DOI - 10.1128/jcm.43.11.5779-5781.2005
Subject(s) - extrapulmonary tuberculosis , mycobacterium tuberculosis , disease , cape , tuberculosis , meningitis , medicine , strain (injury) , pediatrics , pulmonary tuberculosis , virology , pathology , geography , archaeology
We studied the association between strain family and extrapulmonary tuberculosis among 285 children presenting to a pediatric hospital. Extrapulmonary disease occurred in 56% of children without known human immunodeficiency virus infection, with meningitis accounting for 22% of the cases. Two strain families, LAM3/F11 and W-Beijing, predominated; but there was no overall association with extrapulmonary disease.