Open AccessClonal Diversity of Metallo-β-Lactamase-Possessing Pseudomonas aeruginosa in Geographically Diverse Regions of Japan
Author(s) -
Soichiro Kimura,
Jimena Alba,
Katsuaki Shiroto,
Reiko Sano,
Yoshihito Niki,
Shigefumi Maesaki,
Koji Akizawa,
Mitsuo Kaku,
Yuji Watanuki,
Yoshikazu Ishii,
Keizo Yamaguchi
Publication year - 2005
Publication title -
journal of clinical microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.349
H-Index - 255
eISSN - 1070-633X
pISSN - 0095-1137
DOI - 10.1128/jcm.43.1.458-461.2005
Subject(s) - pseudomonas aeruginosa , microbiology and biotechnology , imipenem , biology , pseudomonadaceae , pseudomonadales , gene , strain (injury) , beta lactamase , genetics , bacteria , escherichia coli , anatomy
The aim of this study was to determine the distribution of metallo-beta-lactamase-producing Pseudomonas aeruginosa in Japan and to investigate the molecular characteristics of resistance gene cassettes including the gene encoding this enzyme. A total of 594 nonduplicate strains of P. aeruginosa isolated from 60 hospitals throughout Japan in 2002 were evaluated. This study indicated that although the prevalence of imipenem-resistant P. aeruginosa has not increased compared to that found in previous studies, clonal distribution of the same strain across Japan is evident.