Open AccessCloning and Characterization of Trichophyton rubrum Genes Encoding Actin, Tri r2, and Tri r4
Author(s) -
Jimin Gao,
Akira Takashima
Publication year - 2004
Publication title -
journal of clinical microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.349
H-Index - 255
eISSN - 1070-633X
pISSN - 0095-1137
DOI - 10.1128/jcm.42.7.3298-3299.2004
Subject(s) - trichophyton rubrum , cloning (programming) , gene , biology , molecular cloning , genetics , microbiology and biotechnology , encoding (memory) , complementary dna , computer science , antifungal , programming language , neuroscience
The three structural genes of Trichophyton rubrum encoding actin (3,429 bp) and two antigens, Tri r2 (2,950 bp) and Tri r4 (3,988 bp), were cloned and characterized. They contained six, four, and five exons, respectively. The T. rubrum actin protein sequence revealed extremely high homology to other fungal actins.