Open AccessUse of the Vitek-1 and Vitek-2 Systems for Detection of Constitutive and Inducible Macrolide Resistance in Group B Streptococci
Author(s) -
Patrick Tang,
Peter Ng,
Ming Lum,
M Skulnick,
G W Small,
Donald E. Low,
Alicia Sarabia,
Tony Mazzulli,
Katherine Wong,
Andrew E. Simor,
Barbara M. Willey
Publication year - 2004
Publication title -
journal of clinical microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.349
H-Index - 255
eISSN - 1070-633X
pISSN - 0095-1137
DOI - 10.1128/jcm.42.5.2282-2284.2004
Subject(s) - erythromycin , clindamycin , microbiology and biotechnology , group b , agar , agar diffusion test , group a , biology , antibiotics , medicine , bacteria , staphylococcus aureus , genetics
A prospective study of erythromycin and clindamycin resistance was performed with 304 consecutive group B streptococci (GBS) isolates. According to two automated susceptibility testing systems, Vitek-1 and Vitek-2, and double-disk agar diffusion, 79.9% were susceptible to both erythromycin and clindamycin. However, for macrolide-lincosamide-streptogramin B-inducible isolates, the accuracies of the Vitek-1 and Vitek-2 systems were 5.6 and 94.4%. In light of these results, we recommend that GBS be routinely tested using the double-disk diffusion method.