Open AccessDistinctiveness of Mycobacterium tuberculosis Genotypes from Human Immunodeficiency Virus Type 1-Seropositive and -Seronegative Patients in Lima, Peru
Author(s) -
Niyaz Ahmed,
Luz Caviedes,
Mahfooz Alam,
K. R. Rao,
Vartul Sangal,
Patricia Sheen,
Robert H. Gilman,
Seyed E. Hasnain
Publication year - 2003
Publication title -
journal of clinical microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.349
H-Index - 255
eISSN - 1070-633X
pISSN - 0095-1137
DOI - 10.1128/jcm.41.4.1712-1716.2003
Subject(s) - genotype , biology , virology , mycobacterium tuberculosis , tuberculosis , virus , genotyping , immunology , sida , human immunodeficiency virus (hiv) , viral disease , medicine , genetics , gene , pathology
Genotypic analysis of Mycobacterium tuberculosis isolates obtained from human immunodeficiency virus type 1 (HIV-1)-seropositive (n = 80) and -seronegative (n = 25) patients from Lima, Peru, revealed two distinct genotypes correlating with the host immune status. While the level of intrastrain diversity of DNA fingerprints of HIV-seropositive isolates was less pronounced, these isolates showed many clonal groupings.