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Corneal Ulcer Caused by the New Fungal SpeciesSarcopodium oculorum
Author(s) -
Josep Guarro,
Ana Luísa Höfling-Lima,
Josepa Gené,
Denise de Freitas,
Patrício Godoy,
Maria Luisa Zorat-Yu,
Luís Zaror,
Olga Fischman
Publication year - 2002
Publication title -
journal of clinical microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.349
H-Index - 255
eISSN - 1070-633X
pISSN - 0095-1137
DOI - 10.1128/jcm.40.8.3071-3075.2002
Subject(s) - natamycin , corneal ulcer , ketoconazole , fluconazole , fungal keratitis , fungus , microbiology and biotechnology , biology , keratitis , mycosis , hypha , itraconazole , flucytosine , antifungal , conidium , dermatology , medicine , botany , immunology , food science
We describe a case of keratitis caused by a new species of the hyphomycetous genus Sarcopodium, S. oculorum. The corneal ulcer developed after 5 months of treatment with corticosteroids in a Brazilian boy diagnosed with allergic conjunctivitis. Fungal hyphae and conidia were detected in corneal scrapings, and repeated cultures were positive for this fungus. The infection was resolved with natamycin and ketoconazole. Eleven antifungals were tested against this fungus, and all except flucytosine and fluconazole showed in vitro activity.

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