Open AccessAre There Naturally Occurring Pleomorphic Bacteria in the Blood of Healthy Humans?
Author(s) -
Richard William McLaughlin,
Hojatollah Vali,
Peter C. K. Lau,
Roger G. E. Palfree,
A. De Ciccio,
Marc Suquet,
Darakhshan Ahmad,
Richard Villemur,
Marcel Desrosiers,
E. C. S. Chan
Publication year - 2002
Publication title -
journal of clinical microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.349
H-Index - 255
eISSN - 1070-633X
pISSN - 0095-1137
DOI - 10.1128/jcm.40.12.4771-4775.2002
Subject(s) - bacteria , biology , microbiology and biotechnology , 16s ribosomal rna , microorganism , flow cytometry , fluorescence in situ hybridization , antibiotics , ribosomal rna , in situ hybridization , gene , genetics , chromosome , gene expression
Dark-field microscopy of blood from healthy individuals revealed the existence of pleomorphic microorganisms. These bacteria exhibited limited growth and susceptibility to antibiotics and could be detected by fluorescent in situ hybridization and flow cytometry. They were further characterized by analysis of their 16S rRNA and gyrB genes.