Open AccessLongitudinal Quantitative Detection by Real-Time PCR of Mycoplasma genitalium in First-Pass Urine of Men with Recurrent Nongonococcal Urethritis
Author(s) -
Takashi Deguchi,
Takashi Yoshida,
Shigeaki Yokoi,
Masayasu Ito,
Masayoshi Tamaki,
Hiroaki Ishiko,
Satoshi Maeda
Publication year - 2002
Publication title -
journal of clinical microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.349
H-Index - 255
eISSN - 1070-633X
pISSN - 0095-1137
DOI - 10.1128/jcm.40.10.3854-3856.2002
Subject(s) - mycoplasma genitalium , urethritis , mycoplasma , mycoplasmataceae , mollicutes , taqman , urine , medicine , chlamydia trachomatis , virology , biology , microbiology and biotechnology , polymerase chain reaction , biochemistry , gene
By using a TaqMan assay we monitored longitudinal changes in Mycoplasma genitalium loads in five men with recurrent M. genitalium-positive nongonococcal urethritis. We observed regrowth of M. genitalium persisting in hosts after treatment and a possible association of the increase in the M. genitalium load with emergence of symptoms and signs of nongonococcal urethritis in four of these patients.