Open AccessEpstein-Barr Virus (EBV) DNA in Sera of Patients with Primary EBV Infection
Author(s) -
KwokHung Chan,
Mun Hon Ng,
W. H. Seto,
Malik Peiris
Publication year - 2001
Publication title -
journal of clinical microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.349
H-Index - 255
eISSN - 1070-633X
pISSN - 0095-1137
DOI - 10.1128/jcm.39.11.4152-4154;2001
Subject(s) - virology , virus , epstein–barr virus , herpesviridae , epstein–barr virus infection , biology , gammaherpesvirinae , dna , polymerase chain reaction , immunology , viral disease , gene , genetics
Detection of Epstein-Barr Virus (EBV) DNA by PCR in serum had a sensitivity of 80%, a specificity of 94%, and positive and negative predictive values of 95 and 79%, respectively, for the diagnosis of primary EBV infection. We suggest that this is a useful addition to the panel of tests used for this purpose.