Chronic conjunctivitis caused by oral anaerobes and effectively treated with systemic metronidazole plus amoxicillin | Zendy

A.J. van Winkelhoff | Zendy; Fatemeh Mashhadi Abbas | Zendy; Morana Pavičić | Zendy; J. de Graaff | Zendy

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Chronic conjunctivitis caused by oral anaerobes and effectively treated with systemic metronidazole plus amoxicillin

Author(s) -

A.J. van Winkelhoff,

Fatemeh Mashhadi Abbas,

Morana Pavičić,

J. de Graaff

Publication year - 1991

Publication title -

journal of clinical microbiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.349

H-Index - 255

eISSN - 1070-633X

pISSN - 0095-1137

DOI - 10.1128/jcm.29.4.723-725.1991

Subject(s) - prevotella intermedia , metronidazole , amoxicillin , peptostreptococcus , microbiology and biotechnology , bacteroides , prevotella , antibiotics , bacteroides fragilis , anaerobic bacteria , medicine , anaerobic exercise , bacteroidaceae , biology , bacteria , periodontitis , porphyromonas gingivalis , genetics , physiology

In this study, we report on a case of refractory, unilateral anaerobic conjunctivitis. The predominant anaerobic flora consisted of Prevotella intermedia (formerly Bacteroides intermedius) and Peptostreptococcus micros. By using the technique of restriction endonuclease fingerprinting of genomic DNA, it was shown that the P. intermedia likely originated from the oral cavity. Topically applied antibiotics had failed to suppress the infection in the past. Successful treatment was achieved after systemic administration of metronidazole plus amoxicillin.

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