Evaluation of the Directigen 1,2,3 Group A Strep Test for diagnosis of streptococcal pharyngitis | Zendy

Nelson P. Moyer | Zendy; Patricia Quinn | Zendy; C A Showalter | Zendy

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Evaluation of the Directigen 1,2,3 Group A Strep Test for diagnosis of streptococcal pharyngitis

Author(s) -

Nelson P. Moyer,

Patricia Quinn,

C A Showalter

Publication year - 1990

Publication title -

journal of clinical microbiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.349

H-Index - 255

eISSN - 1070-633X

pISSN - 0095-1137

DOI - 10.1128/jcm.28.7.1661-1663.1990

Subject(s) - pharyngitis , medicine , group a , incidence (geometry) , group b , predictive value , positive predicative value , streptococcaceae , population , diagnostic test , gastroenterology , microbiology and biotechnology , pediatrics , antibiotics , biology , physics , environmental health , optics

The Directigen 1,2,3 Group A Strep Test (DGAST; BBL Microbiology Systems, Cockeysville, Md.) was compared with conventional culture methods for the detection of group A streptococci. Among 327 children, the DGAST has a sensitivity of 75.0%, a specificity of 99.1%, and positive and negative predictive values of 97.5 and 89.3%, respectively, as compared with 48-h culture results. The lower sensitivity (60.0%) in 322 adults was related to the low incidence of group A streptococcal pharyngitis in that population (7.8%). The positive and negative predictive values for adults were 93.8 and 96.7%, respectively. Only 3 of 327 (0.9%) pediatric and 2 of 322 (0.6%) adult specimens yielded uninterpretable results in the DGAST.

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