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Tests with 2,713 bacterial isolates (members of the family Enterobacteriaceae and gram-positive cocci) from 14 laboratories compared cefoxitin MICs with cefotetan MICs. Strains that were susceptible to cefoxitin could be assumed to be susceptible to cefotetan. Over half of the cefoxitin-resistant isolates of the Enterobacteriaceae were susceptible to cefotetan.

Cross susceptibility and absence of cross resistance to cefotetan and cefoxitin