Comparison of enzyme-linked immunosorbent assay for acute measles with hemagglutination inhibition complement fixation, and fluorescent-antibody methods | Zendy

Martin B. Kleiman | Zendy; Carol K.L. Blackburn | Zendy; S E Zimmerman | Zendy; M L French | Zendy

Open Access

Comparison of enzyme-linked immunosorbent assay for acute measles with hemagglutination inhibition complement fixation, and fluorescent-antibody methods

Author(s) -

Martin B. Kleiman,

Carol K.L. Blackburn,

S E Zimmerman,

M L French

Publication year - 1981

Publication title -

journal of clinical microbiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.349

H-Index - 255

eISSN - 1070-633X

pISSN - 0095-1137

DOI - 10.1128/jcm.14.2.147-152.1981

Subject(s) - complement fixation test , hemagglutination assay , serology , antibody , measles , virology , titer , hemagglutination , biology , antibody titer , microbiology and biotechnology , immunology , vaccination

An enzyme-linked immunosorbent assay (ELISA) using commercially available reagents was compared with standard serological tests for determination of antibody titers in patients with acute measles. The measles-specific ELISA was as sensitive as complement fixation, hemagglutination inhibition, and indirect fluorescent-antibody methods. The ELISA method used was simple, sensitive, inexpensive, and reproducible and may conveniently be used in a small clinical laboratory.

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