Open AccessAutomated immunofluorescence test for toxoplasmosis
Author(s) -
Morris Gordon,
R A Duncan,
L C Kingsley
Publication year - 1981
Publication title -
journal of clinical microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.349
H-Index - 255
eISSN - 1070-633X
pISSN - 0095-1137
DOI - 10.1128/jcm.13.2.283-285.1981
Subject(s) - toxoplasmosis , fluorometer , immunofluorescence , direct fluorescent antibody , titer , fluorescence , pathology , antigen , antibody , biology , chromatography , medicine , chemistry , immunology , optics , physics
A soluble-antigen fluorescent-antibody technique for serodiagnosis of toxoplasmosis, employing a special fluorometer (FIAX; International Diagnostic Technology, Santa Clara, Calif.), was evaluated in comparison with a standard indirect fluorescent-antibody method which uses a fluorescence microscope. Titers obtained by the new method on 324 serum samples correlated very well with those of the conventional procedure. There was good intralaboratory and interlaboratory agreement in runs on selected samples. The FIAX method is simple, rapid, and reliable and has the advantage of objectivity.
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