The Geographic Origin of Helicobacter pylori Influences the Association of the homB Gene with Gastric Cancer | Zendy

Jieun Kang | Zendy; Kathleen R. Jones | Zendy; Sungil Jang | Zendy; Cara Olsen | Zendy; YunJung Yoo | Zendy; D. Scott Merrell | Zendy; JeongHeon Cha | Zendy

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The Geographic Origin of Helicobacter pylori Influences the Association of the homB Gene with Gastric Cancer

Author(s) -

Jieun Kang,

Kathleen R. Jones,

Sungil Jang,

Cara Olsen,

YunJung Yoo,

D. Scott Merrell,

JeongHeon Cha

Publication year - 2011

Publication title -

journal of clinical microbiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.349

H-Index - 255

eISSN - 1070-633X

pISSN - 0095-1137

DOI - 10.1128/jcm.06293-11

Subject(s) - caga , helicobacter pylori , allele , locus (genetics) , biology , genetics , gene , population , cancer , medicine , virulence , environmental health

We found that South Korean Helicobacter pylori isolates predominantly carry homB at locus B and that there is no association between the homB allele and the cagA allele or the development of gastric cancer within this population. Uniquely, several East Asian strains carried multiple copies of the hom genes.

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