Sensitive and Specific Modified Hodge Test for KPC and Metallo-Beta- Lactamase Detection in Pseudomonas aeruginosa by Use of a Novel Indicator Strain, Klebsiella pneumoniae ATCC 700603 | Zendy

Fernando Pasterán | Zendy; Omar Véliz | Zendy; Melina Rapoport | Zendy; Leonor Guerriero | Zendy; Alejandra Corso | Zendy

Open Access

Sensitive and Specific Modified Hodge Test for KPC and Metallo-Beta- Lactamase Detection in Pseudomonas aeruginosa by Use of a Novel Indicator Strain, Klebsiella pneumoniae ATCC 700603

Author(s) -

Fernando Pasterán,

Omar Véliz,

Melina Rapoport,

Leonor Guerriero,

Alejandra Corso

Publication year - 2011

Publication title -

journal of clinical microbiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.349

H-Index - 255

eISSN - 1070-633X

pISSN - 0095-1137

DOI - 10.1128/jcm.05602-11

Subject(s) - klebsiella pneumoniae , pseudomonas aeruginosa , microbiology and biotechnology , strain (injury) , repeatability , pseudomonadaceae , escherichia coli , biology , pseudomonadales , beta lactamase , enterobacteriaceae , klebsiella , bacteria , chemistry , chromatography , gene , genetics , anatomy

We evaluated the ability of the modified Hodge test to discriminate between KPC- and metallo-beta-lactamase (MBL)-producing Pseudomonas aeruginosa isolates and carbapenemase nonproducers. With Escherichia coli ATCC 25922 as the indicator strain, the MHT resulted in low sensitivity, specificity, and repeatability. Replacing the indicator strain with Klebsiella pneumoniae ATCC 700603 led to an improved performance (100%, 97%, 0%, and 100% sensitivity, specificity, indeterminate results and repeatability, respectively).

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