Open Access“Mycobacterium tilburgii” Infection in Two Immunocompromised Children: Importance of Molecular Tools in Culture-Negative Mycobacterial Disease Diagnosis
Author(s) -
Nico G. Hartwig,
Adilia Warris,
Esther van de Vosse,
Adri G. M. van der Zanden,
Tanja Schülin-Casonato,
Jakko van Ingen,
Rob van Hest
Publication year - 2011
Publication title -
journal of clinical microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.349
H-Index - 255
eISSN - 1070-633X
pISSN - 0095-1137
DOI - 10.1128/jcm.05460-11
Subject(s) - mycobacterium , mycobacterium infections , disease , microbiology and biotechnology , biology , virology , medicine , immunology , bacteria , pathology , genetics
"Mycobacterium tilburgii" is a nontuberculous mycobacterium that cannot be cultured by current techniques. It is described as causing disseminated disease in adults. We present the first cases of disseminated disease in 2 immunocompromised children. This paper stresses the importance of molecular techniques for correct mycobacterial identification and guidance to immunological diagnosis.