Disseminated Rhinovirus C8 Infection with Infectious Virus in Blood and Fatal Outcome in a Child with Repeated Episodes of Bronchiolitis | Zendy

Julien Lupo | Zendy; Isabelle Schuffenecker | Zendy; Christine Morel-Baccard | Zendy; Julie Bardet | Zendy; Valérie Payen | Zendy; Laurent Kaiser | Zendy; Samuel Constant | Zendy; Johannes Alexander Lobrinus | Zendy; Nathalie Lin-Marq | Zendy; Bruno Lina | Zendy; Patrice Morand | Zendy; Caroline Tapparel | Zendy

Open Access

Disseminated Rhinovirus C8 Infection with Infectious Virus in Blood and Fatal Outcome in a Child with Repeated Episodes of Bronchiolitis

Author(s) -

Julien Lupo,

Isabelle Schuffenecker,

Christine Morel-Baccard,

Julie Bardet,

Valérie Payen,

Laurent Kaiser,

Samuel Constant,

Johannes Alexander Lobrinus,

Nathalie Lin-Marq,

Bruno Lina,

Patrice Morand,

Caroline Tapparel

Publication year - 2015

Publication title -

journal of clinical microbiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.349

H-Index - 255

eISSN - 1070-633X

pISSN - 0095-1137

DOI - 10.1128/jcm.03484-14

Subject(s) - rhinovirus , bronchiolitis , common cold , virus , respiratory tract , medicine , virology , respiratory system , respiratory tract infections , respiratory disease , immunology , biology , lung

We report a fatal case of acute lower respiratory tract disease with human rhinovirus C (HRV-C) as the unique cause in a 19-month-old girl with a history of repeated episodes of bronchiolitis. HRV-C type 8 nucleic acids were observed in respiratory, stool, and cerebrospinal fluid samples, and infectious virions were isolated from patient serum after inoculation onto reconstituted airway epithelia.

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