Mycobacterium smegmatis in Skin Biopsy Specimens from Patients with Suppurative Granulomatous Inflammation
Author(s) -
Zhe Xu,
Di Lu,
Xia Zhang,
Haijing Li,
Shufang Meng,
Yuesong Pan,
Alan S. Boyd,
Lin Ma,
YiWei Tang
Publication year - 2013
Publication title -
journal of clinical microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.349
H-Index - 255
eISSN - 1070-633X
pISSN - 0095-1137
DOI - 10.1128/jcm.03421-12
Subject(s) - biopsy , odds ratio , mycobacterium smegmatis , pathology , skin biopsy , granuloma , confidence interval , granulomatous inflammation , medicine , biology , tuberculosis , mycobacterium tuberculosis
Formalin-fixed, paraffin-embedded skin biopsy specimens, including 72 suppurative granulomatous inflammation (SGI) and 47 non-SGI controls, were tested for mycobacteria by using a broad-range PCR and a suspension array identification system. Mycobacterium smegmatis was detected in 13 (18.1%) of the SGI skin biopsy specimens, which was significantly more than 2 (4.3%) in the controls (odds ratio, 5.73; 95% confidence interval, 1.21 to 27.06; P = 0.028).
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