Differential Immunodetection of Toxin B from Highly Virulent Clostridium difficile BI/NAP-1/027 | Zendy

Nira R. Pollock | Zendy; Linan Song | Zendy; Mingwei Zhao | Zendy; David C. Duffy | Zendy; Xinhua Chen | Zendy; Susan P. Sambol | Zendy; Dale N. Gerding | Zendy; Ciarán P. Kelly | Zendy

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Differential Immunodetection of Toxin B from Highly Virulent Clostridium difficile BI/NAP-1/027

Author(s) -

Nira R. Pollock,

Linan Song,

Mingwei Zhao,

David C. Duffy,

Xinhua Chen,

Susan P. Sambol,

Dale N. Gerding,

Ciarán P. Kelly

Publication year - 2015

Publication title -

journal of clinical microbiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.349

H-Index - 255

eISSN - 1070-633X

pISSN - 0095-1137

DOI - 10.1128/jcm.03419-14

Subject(s) - clostridium difficile , nap , virulence , microbiology and biotechnology , toxin , clostridium difficile toxin a , clostridium difficile toxin b , clostridium , biology , clostridiaceae , immunoassay , pore forming toxin , virology , bacteria , microbial toxins , antibiotics , immunology , gene , antibody , genetics , neuroscience

We developed a simple immunoassay capable of differentially detecting toxin B from highly virulent strains ofClostridium difficile (BI/NAP-1/027) in stool. This assay can simultaneously confirm the presence ofin vivo toxin production and provide strain-related information relevant to infection control epidemiology and disease prognosis.

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