Evaluation of the Cepheid Xpert GBS Assay for Rapid Detection of Group B Streptococci in Amniotic Fluids from Pregnant Women with Premature Rupture of Membranes | Zendy

Nadège BourgeoisNicolaos | Zendy; AnneGaël Cordier | Zendy; Christelle Guillet-Caruba | Zendy; François Casanova | Zendy; Alexandra Benachi | Zendy; Florence DoucetPopulaire | Zendy

Open Access

Evaluation of the Cepheid Xpert GBS Assay for Rapid Detection of Group B Streptococci in Amniotic Fluids from Pregnant Women with Premature Rupture of Membranes

Author(s) -

Nadège BourgeoisNicolaos,

AnneGaël Cordier,

Christelle Guillet-Caruba,

François Casanova,

Alexandra Benachi,

Florence DoucetPopulaire

Publication year - 2013

Publication title -

journal of clinical microbiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.349

H-Index - 255

eISSN - 1070-633X

pISSN - 0095-1137

DOI - 10.1128/jcm.03356-12

Subject(s) - group b , amniotic fluid , medicine , streptococcus agalactiae , obstetrics , premature rupture of membranes , group a , pregnancy , antibiotics , streptococcus , microbiology and biotechnology , gestation , fetus , biology , bacteria , genetics

The Xpert GBS real-time PCR assay for the detection of group B streptococci (GBS) in antepartum screening samples was evaluated on amniotic fluid samples collected from 139 women with premature rupture of membrane at term. When any intrapartum positive result from the Xpert GBS or culture was considered a true positive, the sensitivities of the Xpert GBS and culture were 92.3% and 84.6%, respectively. This assay could enhance exact identification of candidates for intrapartum antibiotic prophylaxis.

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