Rapid Ertapenem Susceptibility Testing and Klebsiella pneumoniae Carbapenemase Phenotype Detection in Klebsiella pneumoniae Isolates by Use of Automated Microscopy of Immobilized Live Bacterial Cells
Author(s) -
CareyAnn D. Burnham,
Rachel A. Frobel,
Monica L. Herrera,
Brian L. Wickes
Publication year - 2014
Publication title -
journal of clinical microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.349
H-Index - 255
eISSN - 1070-633X
pISSN - 0095-1137
DOI - 10.1128/jcm.03255-13
Subject(s) - klebsiella pneumoniae , ertapenem , microbiology and biotechnology , klebsiella , enterobacteriaceae , biology , bacteria , antibiotic resistance , antibiotics , escherichia coli , meropenem , gene , genetics , biochemistry
We evaluated detection of ertapenem (ETP) resistance and Klebsiella pneumoniae carbapenemase (KPC) in 47 Klebsiella pneumoniae isolates using a novel automated microscopy system. Automated microscopy correctly classified 22/23 isolates as ETP resistant and 24/24 as ETP susceptible and correctly classified 21/21 isolates as KPC positive and 26/26 as KPC negative.
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