Comparison of GenomEra C. difficile and Xpert C. difficile as Confirmatory Tests in a Multistep Algorithm for Diagnosis of Clostridium difficile Infection | Zendy

Luís Alcalá | Zendy; Elena Reigadas | Zendy; Mercedes Marı́n | Zendy; Antonia Fernández-Chico | Zendy; Pilar Catalán | Zendy; Emilio Bouza | Zendy

Open Access

Comparison of GenomEra C. difficile and Xpert C. difficile as Confirmatory Tests in a Multistep Algorithm for Diagnosis of Clostridium difficile Infection

Author(s) -

Luís Alcalá,

Elena Reigadas,

Mercedes Marı́n,

Antonia Fernández-Chico,

Pilar Catalán,

Emilio Bouza

Publication year - 2014

Publication title -

journal of clinical microbiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.349

H-Index - 255

eISSN - 1070-633X

pISSN - 0095-1137

DOI - 10.1128/jcm.03093-14

Subject(s) - clostridium difficile , predictive value , c difficile , medicine , algorithm , clostridium infections , positive predicative value , gastroenterology , microbiology and biotechnology , computer science , biology , antibiotics

We compared two multistep diagnostic algorithms based on C. Diff Quik Chek Complete and, as confirmatory tests, GenomEraC. difficile and XpertC. difficile . The sensitivity, specificity, positive predictive value, and negative predictive value were 87.2%, 99.7%, 97.1%, and 98.3%, respectively, for the GenomEra-based algorithm and 89.7%, 99.4%, 95.5%, and 98.6%, respectively, for the Xpert-based algorithm. GenomEra represents an alternative to Xpert as a confirmatory test of a multistep algorithm forClostridium difficile infection (CDI) diagnosis.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research