Diagnosis of Clostridium difficile Infections in Children | Zendy

Stella Antonara | Zendy; Amy L. Leber | Zendy

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Diagnosis of Clostridium difficile Infections in Children

Author(s) -

Stella Antonara,

Amy L. Leber

Publication year - 2016

Publication title -

journal of clinical microbiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.349

H-Index - 255

eISSN - 1070-633X

pISSN - 0095-1137

DOI - 10.1128/jcm.03014-15

Subject(s) - clostridium difficile , diagnostic test , clostridium , medicine , biology , immunology , intensive care medicine , pediatrics , microbiology and biotechnology , antibiotics , genetics , bacteria

The detection and diagnosis of Clostridium difficile infection in pediatric populations have some unique considerations in comparison to testing in adults. The testing methodologies, including toxigenic culture, cell cytotoxicity, antigen detection, and, more recently, molecular testing, are the same in all age groups. However, limited data exist on the specific performance characteristics in children. In this review, we focus on the challenges of testing in pediatric populations and assess the available data on test performance in these populations. Additionally, a review of the existing guidance for testing is provided.

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