Evaluation of an Immunochromatographic Assay for Rapid Detection of Penicillin-Binding Protein 2a in Human and Animal Staphylococcus intermedius Group, Staphylococcus lugdunensis, and Staphylococcus schleiferi Clinical Isolates | Zendy

Amanda R. Arnold | Zendy; CareyAnn D. Burnham | Zendy; Bradley Ford | Zendy; Sara D. Lawhon | Zendy; Sigrid K. McAllister | Zendy; David Lonsway | Zendy; Valérie Albrecht | Zendy; Robert C. Jerris | Zendy; J. Kamile Rasheed | Zendy; Brandi Limbago | Zendy; E. M. Burd | Zendy; Lars F. Westblade | Zendy

Open Access

Evaluation of an Immunochromatographic Assay for Rapid Detection of Penicillin-Binding Protein 2a in Human and Animal Staphylococcus intermedius Group, Staphylococcus lugdunensis, and Staphylococcus schleiferi Clinical Isolates

Author(s) -

Amanda R. Arnold,

CareyAnn D. Burnham,

Bradley Ford,

Sara D. Lawhon,

Sigrid K. McAllister,

David Lonsway,

Valérie Albrecht,

Robert C. Jerris,

J. Kamile Rasheed,

Brandi Limbago,

E. M. Burd,

Lars F. Westblade

Publication year - 2015

Publication title -

journal of clinical microbiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.349

H-Index - 255

eISSN - 1070-633X

pISSN - 0095-1137

DOI - 10.1128/jcm.02869-15

Subject(s) - staphylococcus lugdunensis , penicillin binding proteins , microbiology and biotechnology , staphylococcus , staphylococcus aureus , biology , staphylococcus intermedius , penicillin , micrococcaceae , staphylococcal infections , bacteria , virology , antibiotics , antibacterial agent , genetics

The performance of a rapid penicillin-binding protein 2a (PBP2a) detection assay, the Alere PBP2a culture colony test, was evaluated for identification of PBP2a-mediated beta-lactam resistance in human and animal clinical isolates of Staphylococcus intermedius group, Staphylococcus lugdunensis, and Staphylococcus schleiferi. The assay was sensitive and specific, with all PBP2a-negative and PBP2a-positive strains testing negative and positive, respectively.

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