Evaluation of MALDI Biotyper Mycobacteria Library v3.0 for Identification of Nontuberculous Mycobacteria | Zendy

Belén RodríguezSánchez | Zendy; M.J. Ruiz-Serrano | Zendy; Adrián Ruíz | Zendy; Markus Timke | Zendy; Markus Kostrzewa | Zendy; Emilio Bouza | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Evaluation of MALDI Biotyper Mycobacteria Library v3.0 for Identification of Nontuberculous Mycobacteria

Author(s) -

Belén RodríguezSánchez,

M.J. Ruiz-Serrano,

Adrián Ruíz,

Markus Timke,

Markus Kostrzewa,

Emilio Bouza

Publication year - 2016

Publication title -

journal of clinical microbiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.349

H-Index - 255

eISSN - 1070-633X

pISSN - 0095-1137

DOI - 10.1128/jcm.02760-15

Subject(s) - nontuberculous mycobacteria , mycobacterium , microbiology and biotechnology , clinical microbiology , identification (biology) , matrix assisted laser desorption/ionization , biology , bacteria , chemistry , genetics , botany , organic chemistry , adsorption , desorption

Matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) has demonstrated its ability to promptly identify nontuberculous mycobacteria using the Mycobacteria Library v2.0. However, some species are particularly difficult to identify reliably using this database, providing a low log(score). In this study, the identification power of an updated Mycobacteria Library (v3.0) has been evaluated. Overall, 109 NTM isolates were analyzed with both databases. The v3.0 database allowed a high-level confidence in the identification [log(score) value, ≥1.8] of 91.7% of the isolates versus 83.5% with the v2.0 version (P< 0.01).

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research