Does the Capsule Interfere with Performance of Matrix-Assisted Laser Desorption Ionization–Time of Flight Mass Spectrometry for Identification of Cryptococcus neoformans and Cryptococcus gattii? | Zendy

Danilo Yamamoto Thomaz | Zendy; Rafaella C. Grenfell | Zendy; Mónica Vidal | Zendy; Mauro Cintra Giudice | Zendy; Gilda Maria Bárbaro Del Negro | Zendy; Luiz Juliano | Zendy; Gil Benard | Zendy; João Nóbrega de Almeida | Zendy

Open Access

Does the Capsule Interfere with Performance of Matrix-Assisted Laser Desorption Ionization–Time of Flight Mass Spectrometry for Identification of Cryptococcus neoformans and Cryptococcus gattii?

Author(s) -

Danilo Yamamoto Thomaz,

Rafaella C. Grenfell,

Mónica Vidal,

Mauro Cintra Giudice,

Gilda Maria Bárbaro Del Negro,

Luiz Juliano,

Gil Benard,

João Nóbrega de Almeida

Publication year - 2015

Publication title -

journal of clinical microbiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.349

H-Index - 255

eISSN - 1070-633X

pISSN - 0095-1137

DOI - 10.1128/jcm.02635-15

Subject(s) - cryptococcus neoformans , cryptococcus gattii , capsule , mass spectrometry , cryptococcosis , cryptococcus , matrix assisted laser desorption/ionization , biology , chromatography , microbiology and biotechnology , matrix (chemical analysis) , desorption , chemistry , botany , organic chemistry , adsorption

We described the impact of the capsule size for Cryptococcus neoformans and Cryptococcus gattii identification at the species level by Bruker matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS). After experimental capsule size modulation, we observed that reducing the capsule size resulted in improved identification by Bruker MALDI-TOF MS across all of the reference strains analyzed.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research