Clinical and Molecular Characterization of Invasive Heteroresistant Vancomycin-Intermediate Staphylococcus aureus Infections in Korean Hospitals
Author(s) -
Eu Suk Kim,
InGyu Bae,
Jeong Eun Cho,
Yun Jung Choi,
IlHwan Kim,
GiSu Kang,
Hye-yun Sin,
KyoungHo Song,
Chulmin Park,
DongGun Lee,
Moonsuk Kim,
Kyoung Un Park,
Hong Bin Kim
Publication year - 2015
Publication title -
journal of clinical microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.349
H-Index - 255
eISSN - 1070-633X
pISSN - 0095-1137
DOI - 10.1128/jcm.02595-15
Subject(s) - staphylococcus aureus , bacteremia , vancomycin , microbiology and biotechnology , micrococcaceae , medicine , staphylococcal infections , staphylococcus , biology , antibiotics , antibacterial agent , bacteria , genetics
Invasive heteroresistant vancomycin-intermediate Staphylococcus aureus (h-VISA) isolates were identified and characterized in 10 Korean hospitals from July 2009 to June 2011. The prevalence of h-VISA infections was 3.3% (42/1,289). Most (41/42) were health care-associated infections caused by strains belonging to sequence type 5. Cases of persistent bacteremia were frequent (17/42), and 30-day mortality was high (16/40).
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