Open AccessEvaluation of the AdvanDx VRE EVIGENE Assay for Detection of vanA in Vancomycin-Resistant Staphylococcus aureus
Author(s) -
Gregory E. Fosheim,
Roberta B. Carey,
Brandi Limbago
Publication year - 2007
Publication title -
journal of clinical microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.349
H-Index - 255
eISSN - 1070-633X
pISSN - 0095-1137
DOI - 10.1128/jcm.02556-06
Subject(s) - staphylococcus aureus , microbiology and biotechnology , vancomycin , micrococcaceae , biology , virology , antibacterial agent , bacteria , antibiotics , genetics
AdvanDx VRE EVIGENE, a commercialvanA /vanB DNA hybridization assay to identify vancomycin-resistant enterococci (VRE), was evaluated for the detection ofvanA inStaphylococcus aureus . Performance was assessed usingS. aureus , VRE, and vancomycin-intermediate and -susceptible isolates. The assay demonstrated 100% sensitivity and specificity when analyzed visually and by optical density.