Fusarium falciforme Vertebral Abscess and Osteomyelitis: Case Report and Molecular Classification
Author(s) -
Srilatha Edupuganti,
Nadine Rouphael,
Aneesh K. Mehta,
Molly E. Eaton,
John G. Heller,
Adam Bressler,
Mary E. Brandt,
Kerry O’Donnell
Publication year - 2011
Publication title -
journal of clinical microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.349
H-Index - 255
eISSN - 1070-633X
pISSN - 0095-1137
DOI - 10.1128/jcm.02547-10
Subject(s) - vertebral osteomyelitis , osteomyelitis , biology , epidural abscess , abscess , multilocus sequence typing , typing , haplotype , keratitis , fusariosis , fusarium , medicine , pathology , dermatology , microbiology and biotechnology , genotype , immunology , genetics , gene
Fusarium is a ubiquitous mold that can cause superficial infections such as keratitis and onychomycosis in immunocompetent humans; however, infections in immunocompromised hosts can be fatal. We report an unusual case of epidural abscess and vertebral osteomyelitis in a patient with an autoimmune disorder who was on long-term glucocorticoids. Multilocus DNA sequence-based typing revealed that the infection was caused by a novel three-locus haplotype of Fusarium falciforme designated FSSC 3+4qqq.
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