Xpert GBS Assay for Rapid Detection of Group B Streptococcus in Gastric Fluid Samples from Newborns | Zendy

Christelle Jost | Zendy; Béatrice Berçot | Zendy; Hervé Jacquier | Zendy; Laurent Raskine | Zendy; Emmanuel Barranger | Zendy; Geneviève Mouchnino | Zendy; Emmanuelle Cambau | Zendy

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Xpert GBS Assay for Rapid Detection of Group B Streptococcus in Gastric Fluid Samples from Newborns

Author(s) -

Christelle Jost,

Béatrice Berçot,

Hervé Jacquier,

Laurent Raskine,

Emmanuel Barranger,

Geneviève Mouchnino,

Emmanuelle Cambau

Publication year - 2013

Publication title -

journal of clinical microbiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.349

H-Index - 255

eISSN - 1070-633X

pISSN - 0095-1137

DOI - 10.1128/jcm.02532-13

Subject(s) - concordance , group b , streptococcus , medicine , streptococcus agalactiae , group a , microbiology and biotechnology , biology , bacteria , genetics

The Xpert GBS real-time PCR assay was applied to gastric fluid samples from 143 newborns, and it detected group B streptococcus (GBS) within 1 h for 16 (11.2%) cases, while microscopic examination detected only 2 cases. The sensitivity and specificity of the Xpert GBS were 80% and 100%, respectively, with regard to 20 cases of GBS colonization or infection. Concordance of Xpert GBS results versus culture was 92.3%. This test detects in a timely manner newborns at risk for invasive GBS disease.

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