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Molecular Characterization of Staphylococcus aureus and Influenza Virus Coinfections in Patients with Fatal Pneumonia
Author(s) -
Amy M. Denison,
Marlene DeLeon-Carnes,
Dianna M. Blau,
Eric C. Shattuck,
Linda K. McDougal,
J. Kamile Rasheed,
Brandi Limbago,
Sherif R. Zaki,
Christopher D. Paddock
Publication year - 2013
Publication title -
journal of clinical microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.349
H-Index - 255
eISSN - 1070-633X
pISSN - 0095-1137
DOI - 10.1128/jcm.02503-13
Subject(s) - staphylococcus aureus , pneumonia , microbiology and biotechnology , virology , virus , orthomyxoviridae , influenza a virus , biology , medicine , bacteria , genetics
Molecular techniques were used to characterize genetic features of Staphylococcus aureus in 66 fatal cases of pneumonia caused by S. aureus and influenza A or B viruses. Nucleic acids were extracted from formalin-fixed, paraffin-embedded tissues. The majority of cases revealed genetic markers for Panton-Valentine leukocidin, mecA, and spa type t008.

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