Genetic Diversity of Burkholderia contaminans Isolates from Cystic Fibrosis Patients in Argentina | Zendy

Pablo Martina | Zendy; Marisa Bettiol | Zendy; Cecilia Vescina | Zendy; Patricia Montanaro | Zendy; M. Constanza Mannino | Zendy; Claudia I. Prieto | Zendy; Carlos Vay | Zendy; Dieter Naumann | Zendy; Juergen Schmitt | Zendy; Osvaldo Yantorno | Zendy; Antonio Lagares | Zendy; Alejandra Bosch | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Genetic Diversity of Burkholderia contaminans Isolates from Cystic Fibrosis Patients in Argentina

Author(s) -

Pablo Martina,

Marisa Bettiol,

Cecilia Vescina,

Patricia Montanaro,

M. Constanza Mannino,

Claudia I. Prieto,

Carlos Vay,

Dieter Naumann,

Juergen Schmitt,

Osvaldo Yantorno,

Antonio Lagares,

Alejandra Bosch

Publication year - 2012

Publication title -

journal of clinical microbiology

Language(s) - Spanish

Resource type - Journals

SCImago Journal Rank - 2.349

H-Index - 255

eISSN - 1070-633X

pISSN - 0095-1137

DOI - 10.1128/jcm.02500-12

Subject(s) - burkholderia cepacia complex , burkholderia cenocepacia , genotyping , burkholderia , microbiology and biotechnology , biology , genetic diversity , cystic fibrosis , outbreak , genotype , population , virology , bacteria , genetics , medicine , gene , environmental health

A total of 120 Burkholderia cepacia complex isolates collected during 2004-2010 from 66 patients in two cystic fibrosis reference centers in Argentina were analyzed. Burkholderia contaminans was the species most frequently recovered (57.6%), followed by Burkholderia cenocepacia (15%), a species distribution not reported so far. The recA-PCR-based techniques applied to the B. contaminans isolates revealed that 85% of the population carried the recA-ST-71 allele. Our results showed the utility of BOX-PCR genotyping in analyzing B. contaminans diversity. This approach allowed us to address clonal transmission during an outbreak and the genetic changes occurring in infecting bacteria over the course of chronic infection.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research