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Invasive Pulmonary Aspergillosis Due to Emericella nidulans var. echinulata, Successfully Cured by Voriconazole and Micafungin
Author(s) -
Jin Yu,
Xiang-dong Mu,
Ruoyu Li
Publication year - 2013
Publication title -
journal of clinical microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.349
H-Index - 255
eISSN - 1070-633X
pISSN - 0095-1137
DOI - 10.1128/jcm.02487-12
Subject(s) - micafungin , voriconazole , aspergillosis , galactomannan , aspergillus nidulans , medicine , mucorales , microbiology and biotechnology , gastroenterology , biology , pathology , antifungal , immunology , mucormycosis , mutant , biochemistry , gene
A 78-year-old male who was undergoing prolonged glucocorticoid treatment experienced cough and expectoration for 2 weeks. Galactomannan antigen analysis and a chest computed tomography (CT) scan suggested a diagnosis of invasive pulmonary aspergillosis. DNA sequencing indicated thatEmericella nidulans var.echinulata was the causative agent. A combination of voriconazole and micafungin successfully treated the illness.

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