Laboratory Evaluation of Three Rapid Diagnostic Tests for Dual Detection of HIV and Treponema pallidum Antibodies | Zendy

Romney M. Humphries | Zendy; Jennifer S. Woo | Zendy; Jun Ho Chung | Zendy; Anita Sokovic | Zendy; Claire C. Bristow | Zendy; Jeffrey D. Klausner | Zendy

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Laboratory Evaluation of Three Rapid Diagnostic Tests for Dual Detection of HIV and Treponema pallidum Antibodies

Author(s) -

Romney M. Humphries,

Jennifer S. Woo,

Jun Ho Chung,

Anita Sokovic,

Claire C. Bristow,

Jeffrey D. Klausner

Publication year - 2014

Publication title -

journal of clinical microbiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.349

H-Index - 255

eISSN - 1070-633X

pISSN - 0095-1137

DOI - 10.1128/jcm.02468-14

Subject(s) - treponema , syphilis , human immunodeficiency virus (hiv) , diagnostic test , antibody , medicine , kappa , syphilis serodiagnosis , virology , immunology , biology , veterinary medicine , mathematics , geometry

The performance of three research-use-only, dual HIV and syphilis rapid diagnostic tests (RDTs) was evaluated for 150 patient serum samples and compared to reference HIV and Treponema pallidum antibody detection methods. The RDTs performed comparably, with sensitivities of 93 to 99% and specificities of 97 to 100%. The kappa statistic between the RDTs was 0.95.

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