Molecular Characterization of a Catalase-Negative Methicillin-Susceptible Staphylococcus aureus subsp. aureus Strain Collected from a Patient with Cutaneous Abscess | Zendy

Michael W. Ellis | Zendy; Ryan C. Johnson | Zendy; Katrina B. Crawford | Zendy; Jeffrey B. Lanier | Zendy; D. Scott Merrell | Zendy

Open Access

Molecular Characterization of a Catalase-Negative Methicillin-Susceptible Staphylococcus aureus subsp. aureus Strain Collected from a Patient with Cutaneous Abscess

Author(s) -

Michael W. Ellis,

Ryan C. Johnson,

Katrina B. Crawford,

Jeffrey B. Lanier,

D. Scott Merrell

Publication year - 2013

Publication title -

journal of clinical microbiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.349

H-Index - 255

eISSN - 1070-633X

pISSN - 0095-1137

DOI - 10.1128/jcm.02455-13

Subject(s) - staphylococcus aureus , microbiology and biotechnology , methicillin resistant staphylococcus aureus , micrococcaceae , strain (injury) , staphylococcal infections , abscess , catalase , biology , bacteria , medicine , enzyme , genetics , biochemistry , anatomy

We describe a cutaneous abscess caused by catalase-negative methicillin-susceptibleStaphylococcus aureus subsp.aureus in a patient who was concomitantly colonized with virulent USA300 methicillin-resistantS. aureus (MRSA). Sequencing of thekatA gene demonstrated a thymine insertion leading to a frameshift mutation and premature truncation of catalase to 21 amino acids.

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