Sensitivity, Specificity, and Reproducibility of the Capilia TB-Neo Assay | Zendy

Monde Muyoyeta | Zendy; Winnie Mwanza | Zendy; Nkatya Kasese | Zendy; Maina Cheeba-Lengwe | Zendy; Maureen Moyo | Zendy; Deborah Kaluba-Milimo | Zendy; Helen Ayles | Zendy

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Sensitivity, Specificity, and Reproducibility of the Capilia TB-Neo Assay

Author(s) -

Monde Muyoyeta,

Winnie Mwanza,

Nkatya Kasese,

Maina Cheeba-Lengwe,

Maureen Moyo,

Deborah Kaluba-Milimo,

Helen Ayles

Publication year - 2013

Publication title -

journal of clinical microbiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.349

H-Index - 255

eISSN - 1070-633X

pISSN - 0095-1137

DOI - 10.1128/jcm.02441-13

Subject(s) - reproducibility , sensitivity (control systems) , virology , biology , medicine , microbiology and biotechnology , chromatography , chemistry , electronic engineering , engineering

The performance of the Capilia TB-Neo assay, a new-generation assay, was assessed by determining its sensitivity, specificity, reproducibility, and cross-reaction with contaminating organisms. The sensitivity and specificity were 99.2 and 96.4% and 89.3 and 100% in pure and mixed-culture isolates, respectively. The kappa statistic was 95.0 and 77.9% in pure and mixed culture isolates, respectively. There was no cross-reaction with contaminating organisms.

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