Rapid Detection of Staphylococcus aureus in Lower Respiratory Tract Secretions from Patients with Suspected Ventilator-Associated Pneumonia: Evaluation of the Cepheid Xpert MRSA/SA SSTI Assay | Zendy

Emilia Cercenado | Zendy; Mercedes Marín | Zendy; Almudena Burillo | Zendy; Pablo MartínRabadán | Zendy; Marisa Rivera | Zendy; Emilio Bouza | Zendy

Open Access

Rapid Detection of Staphylococcus aureus in Lower Respiratory Tract Secretions from Patients with Suspected Ventilator-Associated Pneumonia: Evaluation of the Cepheid Xpert MRSA/SA SSTI Assay

Author(s) -

Emilia Cercenado,

Mercedes Marín,

Almudena Burillo,

Pablo MartínRabadán,

Marisa Rivera,

Emilio Bouza

Publication year - 2012

Publication title -

journal of clinical microbiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.349

H-Index - 255

eISSN - 1070-633X

pISSN - 0095-1137

DOI - 10.1128/jcm.02409-12

Subject(s) - staphylococcus aureus , respiratory tract , medicine , pneumonia , microbiology and biotechnology , respiratory tract infections , respiratory system , predictive value , micrococcaceae , lower respiratory tract infection , antibacterial agent , antibiotics , biology , bacteria , genetics

A preclinical evaluation was conducted to evaluate the performance of the Cepheid Xpert assay on 135 lower respiratory tract secretions for detection of methicillin-resistantStaphylococcus aureus andS. aureus . Compared with the quantitative culture, the sensitivity, specificity, and positive and negative predictive values were 99.0%, 72.2%, 90.7%, and 96.3%, respectively.

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