Evaluation of the Lyra Direct Strep Assay To Detect Group A Streptococcus and Group C and G Beta-Hemolytic Streptococcus from Pharyngeal Specimens | Zendy

Bobby L. Boyanton | Zendy; Elizabeth M. Darnell | Zendy; Anne E. Prada | Zendy; Dana M. Hansz | Zendy; Barbara Robinson-Dunn | Zendy

Open Access

Evaluation of the Lyra Direct Strep Assay To Detect Group A Streptococcus and Group C and G Beta-Hemolytic Streptococcus from Pharyngeal Specimens

Author(s) -

Bobby L. Boyanton,

Elizabeth M. Darnell,

Anne E. Prada,

Dana M. Hansz,

Barbara Robinson-Dunn

Publication year - 2015

Publication title -

journal of clinical microbiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.349

H-Index - 255

eISSN - 1070-633X

pISSN - 0095-1137

DOI - 10.1128/jcm.02405-15

Subject(s) - streptococcus , group a , streptococcaceae , microbiology and biotechnology , group b , streptococcus bovis , streptococcus pyogenes , antigen , biology , bacteria , medicine , immunology , antibiotics , staphylococcus aureus , genetics , rumen , food science , fermentation

The Lyra Direct strep assay was compared to culture for its ability to detect Streptococcus group A and β-hemolytic groups C/G using rapid antigen-negative pharyngeal specimens (n = 161). The Lyra assay correctly detected all β-hemolytic streptococci (group A, n = 19; group C/G, n = 5). In batch mode, the Lyra assay reduced intralaboratory turnaround time by 60% (18.1 h versus 45.0 h) but increased hands-on time by 96% (3 min 16 s versus 1 min 40 s per specimen).

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