Open AccessGenetic Polymorphisms Influence Plasmodium ovale PCR Detection Accuracy
Author(s) -
Adriana Calderaro,
Giovanna Piccolo,
Francesca Perandin,
Chiara Gorrini,
Simona Peruzzi,
C. Zuelli,
L. Ricci,
N. Manca,
G. Dettori,
Carlo Chezzi,
Georges Snounou
Publication year - 2007
Publication title -
journal of clinical microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.349
H-Index - 255
eISSN - 1070-633X
pISSN - 0095-1137
DOI - 10.1128/jcm.02316-06
Subject(s) - plasmodium ovale , plasmodium malariae , biology , nested polymerase chain reaction , virology , plasmodium (life cycle) , primer (cosmetics) , polymerase chain reaction , malaria , medicine , genetics , plasmodium falciparum , immunology , gene , parasite hosting , plasmodium vivax , chemistry , world wide web , computer science , organic chemistry
Detection ofPlasmodium ovale by use of a nested PCR assay with a novelPlasmodium ovale primer set was superior to detection ofPlasmodium ovale by real-time PCR assays. Nested PCR was also better at detectingP. malariae . The detection ofP. ovale in many patients first admitted >2 months following their return to Italy indicated thatP. ovale relapses are common.
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