Open AccessImpact of Discrepancies between the Abbott RealTime and Cobas TaqMan Assays for Quantification of Human Immunodeficiency Virus Type 1 Group M Non-B Subtypes
Author(s) -
Marc Wirden,
Roland Tubiana,
Françoise Marguet,
Isabelle Leroy,
Anne Simon,
Manuela Bonmarchand,
Zaïna Ait-Arkoub,
Robert L. Murphy,
AnneGeneviève Marcelin,
Christine Katlama,
Vincent Cálvez
Publication year - 2009
Publication title -
journal of clinical microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.349
H-Index - 255
eISSN - 1070-633X
pISSN - 0095-1137
DOI - 10.1128/jcm.02134-08
Subject(s) - taqman , virology , human immunodeficiency virus (hiv) , virus , biology , real time polymerase chain reaction , medicine , microbiology and biotechnology , genetics , gene
Viral loads in 249 clinical samples from individual patients infected with human immunodeficiency virus type 1 non-B subtypes were determined with both the Abbott RealTime and Cobas TaqMan assays. The differences exceeded 0.5 log for about 20% of samples and 1 log for 3%, with higher values always from the Abbott assay in the latter cases.